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Bad mood7/29/2023 ![]() For example, IBD is caused by dysfunction in the interactions between microbes (bacteria), the gut lining, and the immune system. Examples of such diseases include: inflammatory bowel disease (IBD), asthma, obesity, metabolic syndrome, diabetes, and cognitive and mood problems. When the balance between the good and bad bacteria is disrupted, diseases may occur. The gut-brain axis offers us a greater understanding of the connection between diet and disease, including depression and anxiety. There is anatomical and physiologic two-way communication between the gut and brain via the vagus nerve. When someone is prescribed an antidepressant such as a selective serotonin reuptake inhibitor (SSRI), the most common side effects are gut-related, and many people temporarily experience nausea, diarrhea, or gastrointestinal problems. In the relatively new field of nutritional psychiatry we help patients understand how gut health and diet can positively or negatively affect their mood. When we consider the connection between the brain and the gut, it's important to know that 90% of serotonin receptors are located in the gut. But what does my gut have to do with my mood? They suggest eating whole foods and avoiding processed and ultra-processed foods that we know cause inflammation and disease. Researchers recommend "fixing the food first" (in other words, what we eat) before trying gut modifying-therapies (probiotics, prebiotics) to improve how we feel. Some examples of ultra-processed foods are soda, sugary or savory packaged snack foods, packaged breads, buns and pastries, fish or chicken nuggets, and instant noodle soups. Some examples of processed foods are canned foods, sugar-coated dried fruits, and salted meat products. These foods are very common in the typical Western diet. It's important to know that ultra-processed foods such as fast foods are manufactured to be extra tasty by the use of such ingredients or additives, and are cost effective to the consumer. Ultra-processed foods contain substances extracted from food (such as sugar and starch), added from food constituents (hydrogenated fats), or made in a laboratory (flavor enhancers, food colorings). What we eat, especially foods that contain chemical additives and ultra-processed foods, affects our gut environment and increases our risk of diseases. Researchers agree that a person's unique microbiome is created within the first 1,000 days of life, but there are things you can do to alter your gut environment throughout your life. The human microbiome, or gut environment, is a community of different bacteria that has co-evolved with humans to be beneficial to both a person and the bacteria.
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